[Use of thrombelastography to guide posttraumatic hemostatic therapy: More coagulation factor concentrates and less allogenic blood transfusion?]

Transfus Clin Biol. 2016 Nov;23(4):205-211. doi: 10.1016/j.tracli.2016.07.002. Epub 2016 Sep 5.
[Article in French]

Abstract

Viscoelastic technics are used for 10 years and include the ROTEM® and the TEG®. These devices that exploit the viscoelastic properties of the clotting blood, allow a rapid and global analysis of the haemostatic process taking into account all the process interfering with haemostasis such as inflammation. It has been shown that the use of these technics in clinical situations such as trauma, postpartum haemorrhage, gastrointestinal bleeding or cardiac surgery may reduce the need for blood product, the cost and perhaps may improve the outcome of the patients. Thanks to a rapid identification of the underlying coagulation deficit, these technics facilitate decision-making during acute care and help to guide the treatment, particularly with coagulation factor's concentrate.

Keywords: Coagulation factors; Facteurs de coagulation; Fibrinogen; Fibrinogène; Haemostasis; Hémostase; Thromboelastometry; Thromboélastométrie.

MeSH terms

  • Blood Coagulation Factors / administration & dosage
  • Blood Coagulation Factors / therapeutic use*
  • Blood Transfusion*
  • Clinical Decision-Making
  • Drug Monitoring / methods
  • Fibrinogen / therapeutic use*
  • Hemorrhage / blood*
  • Hemorrhage / drug therapy
  • Hemorrhage / etiology
  • Hemorrhage / therapy
  • Hemostasis / physiology*
  • Hemostatic Techniques*
  • Hemostatics / therapeutic use
  • Humans
  • Plasma
  • Postoperative Hemorrhage / blood
  • Postoperative Hemorrhage / drug therapy
  • Postoperative Hemorrhage / etiology
  • Postoperative Hemorrhage / therapy
  • Postpartum Hemorrhage / blood
  • Postpartum Hemorrhage / drug therapy
  • Postpartum Hemorrhage / etiology
  • Postpartum Hemorrhage / therapy
  • Thrombelastography* / instrumentation
  • Wounds and Injuries / complications*

Substances

  • Blood Coagulation Factors
  • Hemostatics
  • prothrombin complex concentrates
  • Fibrinogen