Choice of Aortic Valve Prosthesis in a Rapidly Aging and Long-Living Society

Ann Thorac Cardiovasc Surg. 2016 Dec 20;22(6):333-339. doi: 10.5761/atcs.oa.16-00104. Epub 2016 Sep 12.

Abstract

Purpose: The aim of this study was to evaluate the long-term results of aortic valve replacement (AVR) with mechanical (M) and bioprosthetic (B) valves as recommended by the Japanese guidelines.

Methods: From April 1995 to March 2014, 366 adult patients underwent AVR. Of these, 127 (35%) patients received M and 239 patients (65%) received B valves. A retrospective analysis of the entire and the selected 124 patients aged 60 to 70 years was carried out.

Results: In patients aged 60 to 70 years, the 15-year survival and freedom from reoperation were 88% ± 7% and 100% for the M group and 34% ± 25% (p <0.001) and 73% ± 14% (p = 0.059) for the B group, respectively. Among propensity score matching of the subgroup, there was no significant difference in survival and freedom from reoperation. The rate of thromboembolism was higher in the M (M: 0.58% vs B: 0.35% patient per year, p <0.001) and the rate of hemorrhage was higher in the M group (M: 0.34% vs B: 0.12% patient per year, p <0.001).

Conclusion: The current strategy of aortic valve choice based on the Japanese guidelines has provided excellent long-term results so far.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aging*
  • Aortic Valve / physiopathology
  • Aortic Valve / surgery*
  • Bioprosthesis*
  • Disease-Free Survival
  • Female
  • Heart Valve Diseases / diagnosis
  • Heart Valve Diseases / physiopathology
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation*
  • Heart Valve Prosthesis*
  • Humans
  • Japan
  • Kaplan-Meier Estimate
  • Logistic Models
  • Longevity
  • Male
  • Middle Aged
  • Patient Selection
  • Postoperative Complications / etiology
  • Postoperative Complications / surgery
  • Propensity Score
  • Prosthesis Design*
  • Prosthesis Failure
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome