The Nordic Consortium for Acute type A Aortic Dissection (NORCAAD): objectives and design

Scand Cardiovasc J. 2016 Oct-Dec;50(5-6):334-340. doi: 10.1080/14017431.2016.1235284. Epub 2016 Sep 26.

Abstract

Objectives: The Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) is a collaborative effort of Nordic cardiac surgery centers to study acute type A aortic dissection (ATAAD). Here, we outline the overall objectives and the design of NORCAAD.

Design: NORCAAD currently consists of eight centers in Denmark, Finland, Iceland and Sweden. Data was collected for patients undergoing surgery for ATAAD from 2005 to 2014. A total of 194 variables were retrospectively collected including demographics, past medical history, preoperative medications, symptoms at presentation, operative variables, complications, bleeding and blood transfusions, need for late reoperations, 30-day mortality and long-term survival.

Results: Information was gathered in the database for 1159 patients, of which 67.6% were male. The mean age was 61.5 ± 12.1 years. The mean follow-up was 3.1 ± 2.9 years with a total of 3535 patient years.

Conclusions: NORCAAD provides a foundation for close collaboration between cardiac surgery centers in the Nordic countries. Substudies in progress include: short-term outcomes, long-term survival, time interval from diagnosis until operation, effects of surgical techniques, malperfusion syndrome, renal failure, bleeding and neurological complications on outcomes and the rate of late reoperations.

Keywords: NORCAAD; Type A aortic dissection; complications; outcome; surgery; survival.

Publication types

  • Multicenter Study

MeSH terms

  • Acute Disease
  • Aged
  • Aortic Aneurysm / diagnosis
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / surgery*
  • Aortic Dissection / diagnosis
  • Aortic Dissection / mortality
  • Aortic Dissection / surgery*
  • Blood Transfusion
  • Databases, Factual
  • Female
  • Humans
  • International Cooperation
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Postoperative Complications / mortality
  • Postoperative Complications / surgery
  • Reoperation
  • Research Design*
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Scandinavian and Nordic Countries / epidemiology
  • Time Factors
  • Treatment Outcome
  • Vascular Surgical Procedures* / adverse effects
  • Vascular Surgical Procedures* / mortality