A molecular arms race: new insights into anti-CRISPR mechanisms

John Mallon; Scott Bailey

doi:10.1038/nsmb.3287

A molecular arms race: new insights into anti-CRISPR mechanisms

Nat Struct Mol Biol. 2016 Sep 6;23(9):765-6. doi: 10.1038/nsmb.3287.

Authors

John Mallon¹, Scott Bailey¹

Affiliation

¹ Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

Abstract

Bacteria and phage co-evolve in a molecular arms race. The crystal structure of the AcrF3-PaCas3 complex sheds light on how phages have found ways to suppress CRISPR-Cas immunity.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Archaea / genetics
CRISPR-Cas Systems*
Clustered Regularly Interspaced Short Palindromic Repeats*
Humans

Abstract

Publication types

MeSH terms

Grants and funding