TRI_tool: a web-tool for prediction of protein-protein interactions in human transcriptional regulation

Bioinformatics. 2017 Jan 15;33(2):289-291. doi: 10.1093/bioinformatics/btw590. Epub 2016 Sep 7.

Abstract

The TRI_tool, a sequence-based web tool for prediction of protein interactions in the human transcriptional regulation, is intended for biomedical investigators who work on understanding the regulation of gene expression. It has an improved predictive performance due to the training on updated, human specific, experimentally validated datasets. The TRI_tool is designed to test up to 100 potential interactions with no time delay and to report both probabilities and binarized predictions.

Availability and implementation: http://www.vin.bg.ac.rs/180/tools/tfpred.php CONTACT: vladaper@vinca.rs; nevenav@vinca.rsSupplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Computational Biology / methods*
  • Gene Expression Regulation*
  • Humans
  • Internet
  • Protein Binding*
  • Software*
  • Transcription, Genetic*