Imaging comparison of tubular and colloid pancreatic adenocarcinoma arising from intraductal papillary mucinous neoplasm on multidetector CT

Clin Imaging. 2016 Nov-Dec;40(6):1195-1199. doi: 10.1016/j.clinimag.2016.08.011. Epub 2016 Aug 16.

Abstract

Purpose: This study aims to compare tubular pancreatic ductal adenocarcinoma (tPDAC) and colloid subtype pancreatic ductal adenocarcinoma (cPDAC) associated with intraductal papillary mucinous neoplasms (IPMNs) on computed tomography.

Methods: An institutional review board-approved retrospective study included patients with either IPMN tPDAC or cPDAC. Enhancing mural nodules (MN), solid component (SC), main pancreatic duct (MPD) diameter, and abrupt change in MPD caliber were evaluated.

Results: A total of 22 patients with cPDAC and 17 patients with tPDAC showed no significant difference in MPD size. MN and SC were seen in cPDAC/tPDAC in 55%/18% and 9%/53%, respectively. Abrupt change in MPD caliber was seen in cPDAC/tPDAC at 18%/59%.

Conclusion: cPDAC and tPDAC differ in the frequency of MN, SC, and changes in MPD caliber.

Keywords: Cancer; Ct; IPMN; Pancreas; Pancreatic cyst.

MeSH terms

  • Adenocarcinoma / diagnostic imaging*
  • Adenocarcinoma / pathology
  • Adenocarcinoma, Mucinous / diagnostic imaging*
  • Adenocarcinoma, Mucinous / pathology
  • Adenocarcinoma, Papillary / diagnostic imaging*
  • Adenocarcinoma, Papillary / pathology
  • Aged
  • Carcinoma, Pancreatic Ductal / diagnostic imaging*
  • Carcinoma, Pancreatic Ductal / pathology
  • Colloids
  • Female
  • Humans
  • Male
  • Multidetector Computed Tomography*
  • Pancreatic Ducts / diagnostic imaging
  • Pancreatic Ducts / pathology
  • Pancreatic Neoplasms / diagnostic imaging*
  • Pancreatic Neoplasms / pathology
  • Retrospective Studies

Substances

  • Colloids