Fluctuation-enhanced sensing with organically functionalized gold nanoparticle gas sensors targeting biomedical applications

Talanta. 2016 Nov 1:160:9-14. doi: 10.1016/j.talanta.2016.06.063. Epub 2016 Jun 29.

Abstract

Detection of volatile organic compounds is a useful approach to non-invasive diagnosis of diseases through breath analysis. Our experimental study presents a newly developed prototype gas sensor, based on organically-functionalized gold nanoparticles, and results on formaldehyde detection using fluctuation-enhanced gas sensing. Formaldehyde was easily detected via intense fluctuations of the gas sensor's resistance, while the cross-influence of ethanol vapor (a confounding factor in exhaled breath, related to alcohol consumption) was negligible.

Keywords: Flicker noise; Fluctuation enhanced sensing; Formaldehyde detection; Organically-functionalized gold nanoparticles.

MeSH terms

  • Breath Tests
  • Formaldehyde / analysis*
  • Formaldehyde / chemistry
  • Gold / chemistry*
  • Metal Nanoparticles / chemistry*
  • Photoelectron Spectroscopy

Substances

  • Formaldehyde
  • Gold