Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach

Int Ophthalmol. 2017 Aug;37(4):1047-1051. doi: 10.1007/s10792-016-0300-x. Epub 2016 Sep 2.

Abstract

The aim of the study was to report the clinical utility of optical coherence tomography angiography (OCT-A) in characterizing and differentiating inflammatory lesions and choroidal neovascularization (CNV) in multifocal choroiditis (MFC). A patient affected by MFC complaining central visual loss and scotoma in his left eye was fully investigated with dye-based angiographies, structural OCT and OCT-A. A reactivation of macular CNV was initially suspected, while OCT-A revealed the absence of any decorrelation signal both over the retinal pigment epithelium (RPE) and between RPE and Bruchs' membrane. OCT-A is a promising tool in detecting inflammatory CNV and in differentiating CNV from primitive inflammatory damage. Finely characterizing the aspect of a lesion allows us to choose the best therapeutic strategy for managing these potentially blinding diseases.

Keywords: Inflammatory choroidal neovascularization; Multifocal choroiditis; Optical coherence tomography angiography; Uveitis.

Publication types

  • Case Reports

MeSH terms

  • Bruch Membrane / pathology
  • Choroid / pathology*
  • Choroidal Neovascularization / diagnosis*
  • Choroidal Neovascularization / etiology
  • Choroiditis / complications
  • Choroiditis / diagnosis*
  • Fluorescein Angiography / methods*
  • Fundus Oculi
  • Humans
  • Male
  • Middle Aged
  • Multifocal Choroiditis
  • Retinal Ganglion Cells / pathology
  • Tomography, Optical Coherence / methods*
  • Visual Acuity