Association Analysis in Rice: From Application to Utilization

Front Plant Sci. 2016 Aug 17:7:1202. doi: 10.3389/fpls.2016.01202. eCollection 2016.

Abstract

Association analysis based on linkage disequilibrium (LD) is an efficient way to dissect complex traits and to identify gene functions in rice. Although association analysis is an effective way to construct fine maps for quantitative traits, there are a few issues which need to be addressed. In this review, we will first summarize type, structure, and LD level of populations used for association analysis of rice, and then discuss the genotyping methods and statistical approaches used for association analysis in rice. Moreover, we will review current shortcomings and benefits of association analysis as well as specific types of future research to overcome these shortcomings. Furthermore, we will analyze the reasons for the underutilization of the results within association analysis in rice breeding.

Keywords: Oryza sativa; association analysis; genotyping; linkage disequilibrium; marker density; phenotyping; population structure.

Publication types

  • Review