Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa

Eur Eat Disord Rev. 2016 Nov;24(6):523-527. doi: 10.1002/erv.2472. Epub 2016 Aug 31.

Abstract

Background: Deficits in neuropsychological functioning have consistently been identified in patients with anorexia nervosa (AN). However, little is known on how decision making in AN patients evolves in response to treatment or whether impairments are reversible.

Method: AN patients (n = 42) completed the Iowa Gambling Task (IGT) upon admission to a 3-month day-hospital treatment programme and at a 1-year follow-up. Patient IGT performance was compared to age-matched controls (n = 46).

Results: AN patients displayed poorer performance on the IGT at admission compared to controls (p < .001). Patients with full remission (n = 31; 73.9%) at the 1-year follow-up improved IGT performance (p = 0.007), and scores were similar compared to controls (p = 0.557). AN patients with partial/no remission at follow-up (n = 11; 26.1%) did not improve IGT scores (p = 0.867).

Conclusions: These findings uphold that enduring remission from AN can reverse decision-making impairments, and they might be most likely explained by clinical state rather than a trait vulnerability. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

Keywords: choice behaviour; cognitive behavioural therapy; cognitive impairments; eating and feeding disorders; longitudinal studies; neuropsychology.

MeSH terms

  • Adult
  • Anorexia Nervosa / physiopathology*
  • Anorexia Nervosa / psychology*
  • Decision Making* / physiology
  • Female
  • Gambling / psychology
  • Humans
  • Male
  • Middle Aged
  • Models, Psychological
  • Neuropsychological Tests
  • Remission Induction
  • Task Performance and Analysis