Advanced lipid technology

J Liposome Res. 2017 Sep;27(3):221-227. doi: 10.1080/08982104.2016.1224898. Epub 2016 Oct 9.

Abstract

Phospholipids and cholesterols are being spotlighted as raw materials for preparing liposomes, one of the key compounds for drug delivery systems (DDS), and as base compounds for converting water-soluble drugs to fat-soluble drugs. Other applications of phospholipids also are being explored. Nippon Fine Chemical, aware of the future of such lipids, has developed new processes for synthesizing and purifying phospholipids and is supplying them on an industrial scale. These products - used worldwide - are highly regarded as raw materials for preparing liposomes. In particular, Nippon Fine Chemical's innovative research led to the development of "Presome®", a base agent that facilitates the preparation of liposome solutions. To further this research, Nippon Fine Chemical has established an "Advanced Lipid Technology".

Keywords: Anti-angeogenic therapy; Presome®; high-purity phospholipids and cholesterols; long circulation.

Publication types

  • Review

MeSH terms

  • Animals
  • Cholesterol / chemistry*
  • Delayed-Action Preparations
  • Drug Industry
  • Humans
  • Hydrophobic and Hydrophilic Interactions
  • Liposomes / chemistry*
  • Phospholipids / chemistry*
  • Solubility

Substances

  • Delayed-Action Preparations
  • Liposomes
  • Phospholipids
  • Cholesterol