Upper airway stimulation therapy: A novel approach to managing obstructive sleep apnea

Ryan J Soose; M Boyd Gillespie

doi:10.1002/lary.26258

Upper airway stimulation therapy: A novel approach to managing obstructive sleep apnea

Laryngoscope. 2016 Sep:126 Suppl 7:S5-8. doi: 10.1002/lary.26258.

Authors

Ryan J Soose¹, M Boyd Gillespie²

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
² Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U.S.A.

PMID: 27572120
DOI: 10.1002/lary.26258

Abstract

Objectives: Review the role of upper airway stimulation (UAS) therapy in the management of moderate to severe obstructive sleep apnea (OSA).

Data sources: A literature search was performed of PubMed and Medline using the search terms clinical trial; obstructive sleep apnea; upper airway stimulation; hypoglossal stimulation; hypoglossal nerve; Inspire; and ImThera.

Review methods: All published clinical trials of currently available devices were reviewed. Unpublished data were excluded.

Results: UAS therapy results in surgical success (AHI decrease of >50% and overall AHI <= 20) in 66% of implanted subjects. In addition, UAS therapy results in significant improvement in daytime sleepiness, snoring, and sleep-related quality of life.

Conclusion: UAS therapy is a valid alternative for select patients with moderate to severe OSA who are unsuccessful users of CPAP therapy. Laryngoscope, 126:S5-S8, 2016.

Keywords: Upper airway stimulation; obstructive sleep apnea; sleep medicine.

Publication types

Review

MeSH terms

Electric Stimulation Therapy
Follow-Up Studies
Forecasting
Humans
Sleep Apnea, Obstructive / therapy*