Schincalide A, a Schinortriterpenoid with a Tricyclo[5.2.1.0(1,6)]decane-Bridged System from the Stems and Leaves of Schisandra incarnate

Org Lett. 2016 Sep 16;18(18):4558-61. doi: 10.1021/acs.orglett.6b02197. Epub 2016 Aug 26.

Abstract

Schincalide A (1), an unprecedented schinortriterpenoid possessing a tricyclo[5.2.1.0(1,6)]decane-bridged system, was isolated from the stems and leaves of Schisandra incarnate. The structure with absolute configuration of 1 was determined by extensive spectroscopic analyses and single-crystal X-ray diffraction. A hypothetical biosynthetic pathway of 1 was postulated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Models, Molecular
  • Molecular Conformation
  • Plant Leaves / chemistry*
  • Plant Stems / chemistry*
  • Polycyclic Compounds / chemistry*
  • Schisandra / chemistry*
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification

Substances

  • Polycyclic Compounds
  • Triterpenes