Effect of care-delivery delay on the survival of Mexican women with breast cancer

Salud Publica Mex. 2016 Apr;58(2):237-50. doi: 10.21149/spm.v58i2.7793.

Abstract

Objective: To estimate the effect of care-delivery delays on survival among women with breast cancer.

Materials and methods: A retrospective analysis of 854 women attending 11 hospitals from 2007-2009 was carried out. Kaplan-Meier estimators and a Cox proportional-risk model were employed.

Results: A total of 10.5% of cases were diagnosed in stage I. 82% of sampled women delayed care for more than 67 days between noticing a symptom and initiating treatment. The median time from receipt of results of the mammography to biopsy was 31 days (IQR 14-56). Compared with those who were in quartile I (Q1), survival was lower among those in Q3 and Q4 (HR=1.68, 95%CI 0.94-3.00; HR=1.76, 95% CI 1.04-2.98, respectively).

Conclusions: To increase survival, it is suggested that the time between receipt of the mammography results and diagnostic biopsy be reduced.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / mortality*
  • Breast Neoplasms / therapy
  • Delayed Diagnosis
  • Delivery of Health Care* / statistics & numerical data
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Mammography
  • Middle Aged
  • Neoplasm Staging
  • Proportional Hazards Models
  • Retrospective Studies
  • Socioeconomic Factors
  • Time-to-Treatment*