Quintuplets: 5 Cases of NEC. Are There Other Risk Factors?

Kavita Nadendla; Amelia Sutton; David Kelly; Reed Dimmitt; Linda Wilkinson; Carroll Harmon; Colin Martin

doi:10.1080/15513815.2016.1214197

Quintuplets: 5 Cases of NEC. Are There Other Risk Factors?

Fetal Pediatr Pathol. 2016;35(6):425-433. doi: 10.1080/15513815.2016.1214197. Epub 2016 Aug 23.

Authors

Kavita Nadendla¹, Amelia Sutton², David Kelly³, Reed Dimmitt⁴, Linda Wilkinson¹, Carroll Harmon⁵, Colin Martin¹

Affiliations

¹ a Surgery , University of Alabama at Birmingham , Birmingham , Alabama , USA.
² b Department of Maternal Fetal Medicine , University of Alabama at Birmingham , Birmingham , Alabama , USA.
³ c Pathology , Children's Hospital of Alabama , Birmingham , Alabama , USA.
⁴ d Gastroenterology and Surgery , University of Alabama at Birmingham , Birmingham , Alabama , USA.
⁵ e Surgery , University of Buffalo , Buffalo , New York , USA.

PMID: 27551982
DOI: 10.1080/15513815.2016.1214197

Abstract

Objective: To review a case of quintuplets with all babies developing necrotizing enterocolitis.

Methods: A retrospective study of preterm quintuplets all developing necrotizing enterocolitis. Clinical outcomes were reviewed.

Results: Quintuplets were born at 24 weeks gestation. Each baby developed NEC and was treated. One baby died. Currently the remaining 4 infants are on full enteral nutrition.

Conclusion: Further studies are needed to better understand this emerging population of multiple birth pregnancy and the frequency of NEC development.

Keywords: Necrotizing enterocolitis; genetics; multiple birth pregnancies; prematurity.

MeSH terms

Enterocolitis, Necrotizing / diagnosis
Enterocolitis, Necrotizing / pathology*
Female
Gestational Age
Humans
Ileum
Infant
Infant, Newborn
Male
Premature Birth / pathology*
Quintuplets*
Retrospective Studies
Risk Factors
Time Factors