Vitamin D and Lung Infection

Infect Immun. 2016 Oct 17;84(11):3094-3096. doi: 10.1128/IAI.00679-16. Print 2016 Nov.

Abstract

Available data suggest that vitamin D plays a role in controlling inflammation in the lungs. However, to date vitamin D-induced production of cathelicidin has not been shown to have an effect on the burden of either viruses or bacteria. Future work should continue to determine the effects of vitamin D-regulated mechanisms in the lung and the possible role of cathelicidin against different pulmonary pathogens in vivo.

MeSH terms

  • Adaptive Immunity / physiology
  • Animals
  • Antimicrobial Cationic Peptides / physiology
  • Cathelicidins
  • Disease Models, Animal
  • Humans
  • Immunity, Innate / physiology
  • Respiratory Tract Infections / immunology
  • Respiratory Tract Infections / physiopathology*
  • Vitamin D / immunology
  • Vitamin D / physiology*
  • Vitamin D Deficiency / immunology
  • Vitamin D Deficiency / physiopathology

Substances

  • Antimicrobial Cationic Peptides
  • Vitamin D
  • Cathelicidins