Non-prescription sale and dispensing of antibiotics in community pharmacies in Zambia

Expert Rev Anti Infect Ther. 2016 Dec;14(12):1215-1223. doi: 10.1080/14787210.2016.1227702. Epub 2016 Sep 9.

Abstract

Background: In Zambia, antibiotics are categorized as prescription-only medicines. Antibiotics dispensed without a prescription pose a public health threat, which is a concern. Consequently, the aim is to ascertain the extent of non-prescription sales and dispensing of antibiotics in community pharmacies in Zambia.

Methods: The practice of non-prescription sale and dispensing were assessed in 73 randomly selected community retail pharmacies, using a structured interviewer-administered questionnaire with simulated case scenarios.

Results: Majority (97%) stated that clients frequently requested non-prescribed antibiotics. Interviewees usually asked clients' indications (94%), counselled on dosing (96%) and suggested changes to antibiotic choices (97%). All (100%) dispensed non-prescribed antibiotics. Commonly dispensed antibiotics included amoxicillin (52%), cotrimoxazole (25%) and metronidazole (23%). Non-prescription sale and dispensing of antibiotics was significantly associated with interviewees' professional qualification in four out of five simulations.

Conclusion: Non-prescription sale and dispensing of antibiotics is widespread in Zambia. Concerted public and professional interventions are needed coupled with stronger regulatory enforcement to reduce this.

Keywords: Antibiotics; Zambia; community pharmacy; dispensing; non-prescription sale.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use*
  • Community Pharmacy Services / legislation & jurisprudence
  • Community Pharmacy Services / statistics & numerical data*
  • Cross-Sectional Studies
  • Government Regulation
  • Humans
  • Pharmacists
  • Prescription Drug Diversion / legislation & jurisprudence
  • Prescription Drug Diversion / statistics & numerical data*
  • Prescription Drug Diversion / trends
  • Prescription Drug Misuse / adverse effects
  • Prescription Drug Misuse / legislation & jurisprudence
  • Prescription Drug Misuse / statistics & numerical data*
  • Self Medication
  • Surveys and Questionnaires
  • Zambia

Substances

  • Anti-Bacterial Agents