Canadian Registry of LVIS Jr for Treatment of Intracranial Aneurysms (CaRLA)

J Neurointerv Surg. 2017 Sep;9(9):849-853. doi: 10.1136/neurintsurg-2016-012611. Epub 2016 Aug 19.

Abstract

Introduction: Stents reduce the rate of angiographic recurrence of intracranial aneurysms. The newest stent for intracranial use is the Low-profile Visible Intraluminal Support device (LVIS Jr).

Objective: To assess the efficacy of the new stent in a multicenter retrospective registry.

Materials and method: Centers across Canada using LVIS Jr were contacted and asked to participate in a retrospective registry of consecutive patients treated with LVIS Jr for intracranial aneurysms between January 2013 and July 2015.

Results: A total of 102 patients, with saccular aneurysms in 100 patients (72 women; age range 21-78 years; mean 56.0 years; median 57.5 years) were treated with a LVIS Jr stent. The mean maximum diameter of the dome and neck of the aneurysm and dome to neck ratios were 8.3 mm±7.7 mm, 4.4 mm±1.9 mm, and 1.86±1.22, respectively. Angiographic complications arose in 23 patients, clinical complications in 9 patients, and only 3% of permanent neurological deficits occurred. Death occurred in 1 patient, unrelated to the stent. The ruptured status of the aneurysms (OR=3.29; p=0.046) and use of LVIS Jr for bailout (OR=2.54; p=0.053) showed a trend towards significant association with higher angiographic complications. At the last available follow-up, 68 class I, 20 class II, and 12 class III results were seen.

Conclusions: The LVIS Jr stent is a safe and effective device for stent-assisted coiling, with 3% permanent neurological complications. Stent-assisted coiling continues to be technically challenging in cases of ruptured aneurysms and bailout situations.

Keywords: Aneurysm; Coil; Device; Intervention; Stent.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Aneurysm, Ruptured / diagnostic imaging
  • Aneurysm, Ruptured / epidemiology*
  • Aneurysm, Ruptured / surgery*
  • Canada / epidemiology
  • Cerebral Angiography / methods
  • Embolization, Therapeutic / methods
  • Endovascular Procedures / methods
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / epidemiology*
  • Intracranial Aneurysm / surgery*
  • Male
  • Middle Aged
  • Recurrence
  • Registries*
  • Retrospective Studies
  • Stents / standards*
  • Treatment Outcome
  • Young Adult