The Influence of Induced Astigmatism on the Depth of Focus

Optom Vis Sci. 2016 Oct;93(10):1228-34. doi: 10.1097/OPX.0000000000000961.

Abstract

Purpose: To evaluate whether an induced astigmatism influences the subjective depth of focus.

Methods: Fifty-one participants aged 18 to 35 years and with a mean spherical equivalent refractive error of -0.51 ± 2.35 DS participated in the study. The accommodation was blocked with three drops of 1% cyclopentolate. Refractive errors were corrected after subjective refraction with a 4-mm artificial pupil. To evaluate the depth of focus (DoF), defocus curves with a spherical range of ±1.5 DS were assessed. The DoF was calculated as the horizontal distance at a threshold level of +0.1 logMAR from the maximum visual acuity (VA). Defocus curves were estimated binocularly during distance (500 cm) and a near vision (40 cm) for two induced axis (ATR in 0° and WTR in 90°) and for a fixed amount of astigmatic defocus of -0.5 DC.

Results: The mean natural DoF was 0.885 ± 0.316 D for far vision and 0.940 ± 0.400 D for near vision. With induced astigmatism, the DoF for far vision was significantly increased to 1.095 ± 0.421 D (p = 0.006, ANOVA) for the WTR astigmatism but not for the ATR astigmatism (1.030 ± 0.395 D; p = 0.164, ANOVA). The induced WTR astigmatism enhanced the DoF for near vision significantly to 1.144 ± 0.338 D (p = 0.04, ANOVA), and DoF with induced ATR astigmatism (0.953 ± 0.318 D) was not significantly different (p = 1.00, ANOVA). ATR-astigmatism reduced VA by +0.08 ± 0.08 logMAR (p < 0.01, t-test).

Conclusions: With an induced WTR astigmatism of -0.5 DC, the DoF can be enhanced in the near viewing distance with a marginal loss in binocular VA. The approach of using induced WTR astigmatism can lead to novel optical treatments for presbyopia.

MeSH terms

  • Accommodation, Ocular / drug effects
  • Adolescent
  • Adult
  • Astigmatism / physiopathology*
  • Cyclopentolate / administration & dosage
  • Depth Perception / physiology*
  • Female
  • Humans
  • Male
  • Mydriatics / administration & dosage
  • Prospective Studies
  • Refraction, Ocular
  • Refractive Errors / physiopathology
  • Vision Tests
  • Visual Acuity / physiology*
  • Young Adult

Substances

  • Mydriatics
  • Cyclopentolate