First molecular evidence of kobuviruses in goats in Italy

Arch Virol. 2016 Nov;161(11):3245-8. doi: 10.1007/s00705-016-3017-2. Epub 2016 Aug 17.

Abstract

By screening 139 rectal swabs collected from either asymptomatic or diarrhoeic goats in Italy, we identified kobuvirus RNA in eight samples (5.8 %). Higher positivity rates were observed in diarrhoeic goats (6.5 %, 3/46) than in asymptomatic animals (5.4 %, 5/93), although the difference was not statistically significant. Based on the analysis of a portion of the 3D gene, four strains were found to share the highest nucleotide (nt) sequence identity with bovine kobuviruses (95.0-98.0 %), which had been detected previously in calves in the UK and Korea. Interestingly, two strains were genetically related to the newly discovered caprine kobuviruses (83.0-97.0 % nt sequence identity), which had been identified in black goats in Korea and in roe deer in Italy. Taken together, these findings demonstrate that kobuviruses are common enteric viruses of goats, although their clinical relevance remains to be investigated.

MeSH terms

  • Animals
  • Asymptomatic Infections*
  • Cluster Analysis
  • Diarrhea / veterinary*
  • Diarrhea / virology
  • Genes, Viral
  • Goat Diseases / virology*
  • Goats / virology*
  • Italy
  • Kobuvirus / isolation & purification*
  • Phylogeny
  • Picornaviridae Infections / veterinary*
  • Picornaviridae Infections / virology
  • Rectum / virology
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid