Clinical features of 10 cases of eyelid sporotrichosis in Jilin Province (Northeast China)

Can J Ophthalmol. 2016 Aug;51(4):297-301. doi: 10.1016/j.jcjo.2016.02.018. Epub 2016 May 10.

Abstract

Objective: Sporotrichosis is a common subcutaneous mycosis caused by an infection with dimorphic fungus Sporothrix schenckii. We present a series of patients with eyelid sporotrichosis and study the clinical and histopathological presentation, microbiology, treatment options, and outcome.

Methods: A retrospective case-series study of patients with a clinical diagnosis of eyelid sporotrichosis. Records were examined to obtain information regarding patient demographics, presenting symptoms and signs, histopathological examination, microbiology, management, and outcomes.

Results: Ten patients (4 men, 6 women; mean age 46.5 years, range 3-81 years) were included. Based on their clinical manifestations, eyelid sporotrichosis was classified into 3 major forms: (i) fixed cutaneous (6/10 cases), (ii) lymphocutaneous (3/10 cases), and (iii) eyelid abscess (1/10 cases). All the cases were treated with a terbinafine 12-week regimen. Nodules, papules, and abscesses regressed after treatment. No recurrence was discovered after a 12-week follow-up.

Conclusions: Eyelid sporotrichosis has typical features of clinical manifestations. Histopathological examination and tissue culture are helpful for diagnosis. Confirmed cases normally require long-term systematic treatment with antifungal agents, but surgical removal is normally unnecessary.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antifungal Agents / therapeutic use
  • Child
  • Child, Preschool
  • China
  • Eye Infections, Fungal / diagnosis*
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / microbiology
  • Eyelid Diseases / diagnosis*
  • Eyelid Diseases / drug therapy
  • Eyelid Diseases / microbiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Naphthalenes / therapeutic use
  • Retrospective Studies
  • Sporothrix / isolation & purification*
  • Sporotrichosis / diagnosis*
  • Sporotrichosis / drug therapy
  • Sporotrichosis / microbiology
  • Terbinafine

Substances

  • Antifungal Agents
  • Naphthalenes
  • Terbinafine