Polyamines: Small Molecules with a Big Role in Promoting Virus Infection

Melody M H Li; Margaret R MacDonald

doi:10.1016/j.chom.2016.07.012

Polyamines: Small Molecules with a Big Role in Promoting Virus Infection

Cell Host Microbe. 2016 Aug 10;20(2):123-4. doi: 10.1016/j.chom.2016.07.012.

Authors

Melody M H Li¹, Margaret R MacDonald²

Affiliations

¹ Laboratory of Virology and Infectious Disease, Rockefeller University, New York, NY 10065, USA.
² Laboratory of Virology and Infectious Disease, Rockefeller University, New York, NY 10065, USA. Electronic address: macdonm@rockefeller.edu.

PMID: 27512896
DOI: 10.1016/j.chom.2016.07.012

Abstract

Polyamines play important roles in a range of cellular processes. In this issue of Cell Host & Microbe, Mounce et al. (2016) link polyamine metabolism to the interferon response and demonstrate proviral effects for polyamines. The study points to the pathway as a potential novel pan-viral therapeutic target.

Publication types

Comment

MeSH terms

Polyamines*

Substances

Polyamines