Profile and Trends of Rotavirus Gastroenteritis in Under 5 children in India, 2012 - 2014, Preliminary Report of the Indian National Rotavirus Surveillance Network

Indian Pediatr. 2016 Jul 8;53(7):619-22. doi: 10.1007/s13312-016-0897-x.

Abstract

Objective: To estimate the burden of rotavirus-associated gastroenteritis in India.

Methods: Hospital based surveillance network was established, with clinical evaluation and laboratory testing for rotavirus among children aged below 5 years hospitalized with acute gastroenteritis.

Results: Between September 2012 and December 2014, stool samples from 10207 children were tested and rotavirus was detected in 39.6% of cases. Infections were more commonly seen among younger children (<2 years). Detection rates were higher during cooler months of September February. Among rotavirus infected children, 64.0% had severe or very severe disease. G1P[8] was the predominant rotavirus genotype (62.7%) observed during the surveillance period.

Conclusions: Surveillance data highlights the high rotavirus disease burden and emphasizes the need for close monitoring to reduce morbidity and mortality associated with rotavirus gastroenteritis in India.

MeSH terms

  • Child, Preschool
  • Diarrhea / epidemiology*
  • Diarrhea / physiopathology
  • Diarrhea / virology
  • Feces / virology
  • Female
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / physiopathology
  • Gastroenteritis / virology
  • Hospitalization / statistics & numerical data
  • Humans
  • India / epidemiology
  • Infant
  • Infant, Newborn
  • Male
  • Prevalence
  • Public Health Surveillance
  • Rotavirus / genetics
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / physiopathology
  • Rotavirus Infections / virology