MicroRNAs of the miR379-410 cluster: New players in embryonic neurogenesis and regulators of neuronal function

Jennifer Winter

doi:10.1080/23262133.2015.1004970

MicroRNAs of the miR379-410 cluster: New players in embryonic neurogenesis and regulators of neuronal function

Neurogenesis (Austin). 2015 Mar 4;2(1):e1004970. doi: 10.1080/23262133.2015.1004970. eCollection 2015.

Author

Jennifer Winter¹

Affiliation

¹ Institute of Human Genetics; University Medical Centre Mainz ; Mainz, Germany.

Abstract

The imprinted miR379-410 cluster contains 38 microRNAs (miRNAs) that are involved in diverse neurodevelopmental processes and are important regulators of neuronal function. The implications of these miRNAs in neurological diseases have been recently recognized.In the present minireview, the current findings regarding the brain-specific functions of miR379-410 cluster miRNAs are summarized and discussed.

Keywords: DLK1-DIO3; N-cadherin; miR-134; miR-369–3p; miR-496; miR-543; miR379–410; neurogenesis; neuronal function.

Publication types

Review