1 Clinical and Experimental Sciences University of Southampton and Southampton General Hospital, Southampton, England. Electronic address: r.a.mackay@soton.ac.uk.
2 Clinical and Experimental Sciences University of Southampton and Southampton General Hospital, Southampton, England; Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia.
3 Clinical and Experimental Sciences University of Southampton and Southampton General Hospital, Southampton, England.
4 Clinical and Experimental Sciences University of Southampton and Southampton General Hospital, Southampton, England; Southampton NIHR Respiratory Biomedical Research Unit, Southampton Centre for Biomedical Research, University Hospital Southampton NHS Foundation Trust, Southampton, England.
5 Southampton NIHR Respiratory Biomedical Research Unit, Southampton Centre for Biomedical Research, University Hospital Southampton NHS Foundation Trust, Southampton, England.