Predictors of Recurrence and Successful Treatment Following Obstetric Fistula Surgery

Urology. 2016 Nov:97:80-85. doi: 10.1016/j.urology.2016.03.079. Epub 2016 Aug 2.

Abstract

Objective: To determine factors contributing to recurrence and successful treatment of obstetric fistula (OF).

Materials and methods: Data were collected from OF patients in Saint Luc Hospital Kisantu (DR of Congo) between 2007 and 2013. Patients underwent surgical treatment and were evaluated after a follow-up period of 3 months. Successful treatment was defined as no or dry pads whereas recurrence was defined as the persisting need for wearing incontinence pads immediately after the surgery or after a period of dryness. Fistula classification was done according to Waaldijk. Univariate and multivariate analyses were performed using logistic regression, corrected for preoperative and intraoperative OF characteristics.

Results: Median age of 166 OF patients was 29.11 ± 9. 6 years (range 5-61). The majority of OF was type I (57.2%) followed by type III (20.5 %). There were 20.5% who showed vaginal fibrosis during surgical treatment. The most common location of fistula was pericervical (39.8%). The global recurrence rate at 3 months was 28.3%, with type IIBb (100%) as most the common recurring, followed by IIAb (66.67%) and IIAa (41.18%). There were 71.7%, 15.7%, 12%, and 0.6% patients who were considered completely cured, partially cured (downstaged), persistent, and upstaged, respectively. OF patients with fibrosis were 68% less likely (odds ratio 0.32, 95% confidence interval 0.14-0.73; P = .0065) to be dry in comparison to those without fibrosis. Patients with urethral fistula were 73% less likely (odds ratio 0.27, 95% confidence interval 0.11-0.63; P = .0024) to be dry compared to other locations.

Conclusion: This study showed that fibrosis and urethral location are independent risk factors for fistula recurrence or persistence following surgical fistula repair.

MeSH terms

  • Adult
  • Analysis of Variance
  • Cohort Studies
  • Congo
  • Databases, Factual
  • Female
  • Humans
  • Incidence
  • Labor, Obstetric
  • Multivariate Analysis
  • Obstetric Labor Complications / diagnosis*
  • Obstetric Labor Complications / epidemiology*
  • Pregnancy
  • Recurrence
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
  • Urogenital Surgical Procedures / methods*
  • Vesicovaginal Fistula / etiology*
  • Vesicovaginal Fistula / physiopathology
  • Vesicovaginal Fistula / surgery*
  • Young Adult