Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection

J Vet Diagn Invest. 2016 Sep;28(5):604-7. doi: 10.1177/1040638716661381. Epub 2016 Aug 4.

Abstract

Listeria monocytogenes, a well-described cause of encephalitis and abortion in ruminants and of food-borne illness in humans, is rarely associated with disease in companion animals. A case of urinary tract infection associated with an atypical, weakly hemolytic L. monocytogenes strain is described in a diabetic dog. The serotype of the L. monocytogenes isolate was determined to be 1/2a (3a), with the multilocus genotyping pattern 2.72_1/2a. A nucleotide substitution (Gly145Asp) was detected at residue 145 in the promoter prfA region. This residue is within the critical helix-turn-helix motif of PrfA. The source of the L. monocytogenes strain remains unknown, and the dog recovered after a 4-week course of cephalexin (30 mg/kg orally twice daily).

Keywords: Canine listeriosis; Listeria monocytogenes; canine urinary tract infection.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / veterinary*
  • Diagnosis, Differential
  • Dog Diseases / diagnosis*
  • Dog Diseases / microbiology
  • Dogs
  • Listeria monocytogenes / isolation & purification*
  • Listeriosis / complications
  • Listeriosis / microbiology
  • Listeriosis / veterinary*
  • Male
  • Urinary Tract Infections / complications
  • Urinary Tract Infections / microbiology
  • Urinary Tract Infections / veterinary*