HLA-A*23:01:19, a novel variant of HLA-A*23:01, discovered in a West African stem cell transplantation patient

HLA. 2016 Sep;88(3):120-1. doi: 10.1111/tan.12849. Epub 2016 Aug 5.

Abstract

HLA-A*23:01:19 differs from HLA-A*23:01:01 by a single substitution in exon 4.

Keywords: HLA-A novel variant; hematopoietic stem cell; human leukocyte antigen; new allele; sequence-based typing.

MeSH terms

  • Africa, Western
  • Alleles*
  • Anemia, Sickle Cell / immunology
  • Anemia, Sickle Cell / pathology
  • Anemia, Sickle Cell / therapy
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • Gene Expression
  • HLA-A Antigens / genetics*
  • HLA-A Antigens / immunology
  • Hematopoietic Stem Cell Transplantation
  • Histocompatibility Testing
  • Humans
  • Polymorphism, Single Nucleotide*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Transplant Recipients*

Substances

  • Codon
  • HLA-A Antigens
  • HLA-A*23:01 antigen