Simple Approach to Synthesize Amino-Functionalized Carbon Dots by Carbonization of Chitosan

Sci Rep. 2016 Aug 5:6:31100. doi: 10.1038/srep31100.

Abstract

Carbon dots (CDs) as a new series of fluorescent nanomaterials have drawn great attention in recent years owning to their unique properties. In this paper, a simple carbonization approach to synthesize amino-functionalized CDs was developed by using chitosan as the carbon precursor. The as-prepared CDs possessed desirable amino function group on their surface and exhibited bright luminescence with absolute quantum yield (QY) of 4.34%, excitation-, pH-dependent and up-conversion fluorescence behaviors. Furthermore, we have investigated the cytotoxicity and biocompatibility of the as-prepared CDs, which demonstrated that the as-prepared CDs have the potential applications in biosensing, cellular imaging and drug delivery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids*
  • Biocompatible Materials*
  • Biosensing Techniques / methods
  • Carbon*
  • Chitosan*
  • Cytological Techniques / methods
  • Drug Delivery Systems
  • Nanostructures / chemistry*

Substances

  • Amino Acids
  • Biocompatible Materials
  • Carbon
  • Chitosan