Effect of Contamination with Perennial Permafrost Microorganisms on the Outcome of Closed Brain Neurotrauma

Bull Exp Biol Med. 2016 Jul;161(3):388-90. doi: 10.1007/s10517-016-3421-3. Epub 2016 Aug 5.

Abstract

We studied the effect of contamination with Bacillus genus microorganisms isolated from perennial permafrost samples on the outcome of closed brain neurotrauma in Wistar rats. It was found that contamination with different Bacillus strains produced different effects on the mortality of experimental animals with closed neurotrauma. The complex of metabolites from strain Ch2/9 - Bacillus spp. (pumilus) produced a protective effect in experimental closed brain neurotrauma.

Keywords: brain; contamination; neurotrauma; strain.

MeSH terms

  • Animals
  • Bacillus / metabolism
  • Bacillus / physiology
  • Brain / microbiology*
  • Brain / pathology
  • Brain Injuries / microbiology*
  • Brain Injuries / pathology*
  • Male
  • Permafrost / microbiology*
  • Rats
  • Rats, Wistar