A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children

BMC Public Health. 2016 Aug 3:15:705. doi: 10.1186/s12889-016-3334-0.

Abstract

Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promote poison prevention practices.

Methods: A probabilistic decision-analytic model simulates healthcare costs and benefits for a hypothetical cohort of under 5 year olds. The model compares the cost-effectiveness of home safety education, home safety inspections, provision of free or low cost safety equipment and fitting of equipment. Analyses are conducted from a UK National Health Service and Personal Social Services perspective and expressed in 2012 prices.

Results: Education without safety inspection, provision or fitting of equipment was the most cost-effective strategy for promoting safe storage of medicines with an incremental cost-effectiveness ratio of £2888 (95 % credible interval (CrI) £1990-£5774) per poison case avoided or £41,330 (95%CrI £20,007-£91,534) per QALY gained compared with usual care. Compared to usual care, home safety interventions were not cost-effective in promoting safe storage of other household products.

Conclusion: Education offers better value for money than more intensive but expensive strategies for preventing medicinal poisonings, but is only likely to be cost-effective at £30,000 per QALY gained for families in disadvantaged areas and for those with more than one child. There was considerable uncertainty in cost-effectiveness estimates due to paucity of evidence on model parameters. Policy makers should consider both costs and effectiveness of competing interventions to ensure efficient use of resources.

Keywords: Children; Decision models; Economic evaluation; Injury prevention; Poisonings; Public health.

Publication types

  • Comparative Study

MeSH terms

  • Child, Preschool
  • Cost-Benefit Analysis*
  • Family Characteristics*
  • Female
  • Health Care Costs*
  • Health Education / economics
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Models, Theoretical
  • Poisoning*
  • Poisons*
  • Protective Devices* / economics
  • Quality-Adjusted Life Years
  • Safety*
  • Social Work
  • Socioeconomic Factors
  • United Kingdom

Substances

  • Poisons