Adenomyoepithelioma of the breast with late pulmonary metastases - case report and review of the literature

J Cardiothorac Surg. 2016 Aug 4;11(1):121. doi: 10.1186/s13019-016-0518-8.

Abstract

Background: Adenomyoepithelioma (AME) of the breast is a rare tumour of unpredictable clinical behaviour. Most of the tumours are benign with some giving local recurrences or distant metastases.

Case presentation: We report a case of late lung metastases in a woman with a history of breast adenomyoepithelioma. Partial lobectomy was performed for lung lesions and initial diagnosis was epithelial-myoepithelial carcinoma.

Conclusion: Careful slide's revision of both breast and pulmonary lesions showed identical microscopic appearance with lung tumour performing more malignant features. Tumour cells in both: breast and pulmonary lesions were positive for cytokeratin and EMA (epithelial cells) and also for SMA, S100 and vimentin (myoepithelial cells). Two years and 7 months follow-up showed no recurrent neoplastic disease in our patient.

Keywords: Adenomyoepithelioma; Breast; Epithelial-myoepithelial carcinoma; Lung.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenomyoepithelioma / pathology
  • Adenomyoepithelioma / secondary
  • Adenomyoepithelioma / surgery*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary
  • Lung Neoplasms / surgery*
  • Middle Aged
  • Pneumonectomy