Ectopic micronodular thymoma with lymphoid stroma in the cervical region: a rare case associated with Langerhans cells proliferation

Onco Targets Ther. 2016 Jul 18:9:4317-22. doi: 10.2147/OTT.S110802. eCollection 2016.

Abstract

Micronodular thymoma (MNT) with lymphoid stroma is a rare thymic epithelial neoplasm with the characteristics of multiple nodules separated by abundant lymphoid stroma. MNTs mainly arise in the anterior mediastinum and thymus, while ectopic MNTs are extremely rarely seen. Here, we report an ectopic MNT that occurred in the neck of a 62-year-old woman. There were also scattered eosinophilic granulocytes and S100(+)/CD1a(+) Langerhans cells within the tumor. This case provides a better understanding of such rare, poorly understood cases.

Keywords: Langerhans cell; ectopic; lymphoid stroma; micronodular thymoma.

Publication types

  • Case Reports