Objective: To evaluate the efficacy and adverse effects of sole percutaneous microwave coagulation therapy (PMCT) compared to that of PMCT combining with transcatheter arterial chemoembolization (TACE) for the treatment of primary hepatoma.
Methods: A total of 50 patients diagnosed with primary hepatocellular carcinoma were recruited and divided into two groups. Group A included 15 patients only treated with PMCT. The other 35 ones falling into group B were treated with PMCT in combination with TACE. Analysis of therapeutic efficacy and adverse effects were conducted.
Results: The objective effect rates in group A and group B were 40.0% and 62.8%, respectively. There was no significant difference between the two groups(P = 0.136). The one-year survival rates of the two groups were 46.6% and 71.4%,respectively(P = 0.095);and the two-year survival rates were 26.7% and 42.8%,respectively (P = 0.048). No grade III adverse effects or beyond were observed.
Conclusion: PCMT combining with TACE is safe and more effective in one-year survival than PCMT alone for the treatment of primary hepatocellular carcinoma.