Epidemiologic studies and novel clinical research approaches that impact TB vaccine development

Thomas G Evans; Gavin J Churchyard; Adam Penn-Nicholson; Chen Chen; Xu Gao; Dereck R Tait; Mark Hatherill

doi:10.1016/j.tube.2016.05.008

Epidemiologic studies and novel clinical research approaches that impact TB vaccine development

Tuberculosis (Edinb). 2016 Aug:99 Suppl 1:S21-5. doi: 10.1016/j.tube.2016.05.008. Epub 2016 Jun 11.

Authors

Thomas G Evans¹, Gavin J Churchyard², Adam Penn-Nicholson³, Chen Chen⁴, Xu Gao⁵, Dereck R Tait⁶, Mark Hatherill³

Affiliations

¹ Aeras, Rockville, MD, USA. Electronic address: tevans@aeras.org.
² Aurum Research Institute, Johannesburg, South Africa; School of Public Health, University of Witwatersrand, South Africa.
³ South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease & Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
⁴ Aeras, Beijing, China.
⁵ Fudan University, Shanghai, China; Heidelberg University, Heidelberg, Germany.
⁶ Aeras, Cape Town, South Africa.

PMID: 27461190
DOI: 10.1016/j.tube.2016.05.008

Abstract

The 4th Global Forum on TB Vaccines, convened in Shanghai, China, from 21 - 24 April 2015, brought together a wide and diverse community involved in tuberculosis vaccine research and development to discuss the current status of, and future directions for this critical effort. This paper summarizes the sessions on Developing TB Vaccines for Prevention of Disease, Prevention of Infection, and Immunotherapy Indications; Concepts and Approaches in Clinical Research & Development; and Epidemiological Research. Summaries of all sessions from the 4th Global Forum are compiled in a special supplement of Tuberculosis.

Keywords: Clinical trial; Epidemiology; Tuberculosis.

Publication types

Congress

MeSH terms

BCG Vaccine
Drug Discovery
Epidemiologic Methods
Humans
Secondary Prevention
Tuberculosis / epidemiology
Tuberculosis / prevention & control*
Tuberculosis Vaccines*

Substances

BCG Vaccine
Tuberculosis Vaccines