Novel approaches to preclinical research and TB vaccine development

Tuberculosis (Edinb). 2016 Aug:99 Suppl 1:S12-5. doi: 10.1016/j.tube.2016.05.012. Epub 2016 Jun 16.

Abstract

The 4th Global Forum on TB Vaccines, convened in Shanghai, China, from 21 - 24 April 2015, brought together a wide and diverse community involved in tuberculosis vaccine research and development to discuss the current status of, and future directions for this critical effort. This paper summarizes the sessions on Low-Dose NHP Challenge Models, Novel Approaches to Animal Models for TB Vaccine R&D, Novel Antigen Delivery Strategies, and Next Generation TB Vaccines and Vaccine Concepts. Summaries of all sessions from the 4th Global Forum are compiled in a special supplement of Tuberculosis. [August 2016, Vol 99, Supp S1, S1-S30].

Keywords: Animal models; TB pathogenesis; Tuberculosis; Vaccines.

Publication types

  • Congress

MeSH terms

  • Aerosols
  • BCG Vaccine / immunology
  • BCG Vaccine / pharmacology
  • Clinical Trials as Topic
  • Drug Delivery Systems
  • Drug Design
  • Drug Discovery
  • Drug Evaluation, Preclinical
  • HLA-E Antigens
  • Histocompatibility Antigens Class I / immunology
  • Humans
  • Tuberculosis / diagnosis
  • Tuberculosis / genetics
  • Tuberculosis / prevention & control*
  • Tuberculosis Vaccines / immunology
  • Tuberculosis Vaccines / pharmacology*
  • Vaccines, Attenuated / immunology
  • Vaccines, Attenuated / pharmacology
  • Vaccines, Synthetic / immunology
  • Vaccines, Synthetic / pharmacology

Substances

  • Aerosols
  • BCG Vaccine
  • Histocompatibility Antigens Class I
  • Tuberculosis Vaccines
  • Vaccines, Attenuated
  • Vaccines, Synthetic