Structural, functional and molecular dynamics analysis of the native and mutated actin to study its effect on congenital myopathy

J Biomol Struct Dyn. 2017 May;35(7):1608-1614. doi: 10.1080/07391102.2016.1190299. Epub 2016 Jul 22.

Authors

Faeze Sadat Mohajer¹, Sepideh Parvizpour², Jafar Razmara³, Mahsa Khoshkhooy Yazdi⁴, Mohd Shahir Shamsir¹

Affiliations

¹ a Bioinformatics Research Group, Faculty of Bioscience and Medical Engineering , UniversitiTeknologi Malaysia , Johor Bahru , Malaysia.
² b Biotechnology Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
³ c Departement of Computer Science , University of Tabriz , Tabriz , Iran.
⁴ d Faculty of Science, Department of Chemistry , Universiti Teknologi Malaysia , 81310 UTM, Johor , Malaysia.

PMID: 27448459
DOI: 10.1080/07391102.2016.1190299

No abstract available

Publication types

Letter

MeSH terms

Actins / chemistry*
Actins / genetics
Cardiac Myosins / chemistry
Cardiac Myosins / genetics
Humans
Molecular Dynamics Simulation*
Muscular Diseases / genetics*
Muscular Diseases / pathology
Mutation
Myosin Heavy Chains / chemistry
Myosin Heavy Chains / genetics
Protein Conformation*
Structure-Activity Relationship*

Substances

Actins
MYH7 protein, human
Cardiac Myosins
Myosin Heavy Chains