MYC and BCL2 evaluation in routine diagnostics of aggressive B-cell lymphomas - presentation of a work-flow and the experience with 248 cases

Br J Haematol. 2017 Nov;179(4):681-684. doi: 10.1111/bjh.14250. Epub 2016 Jul 22.

Authors

Thomas Menter^{1

2}, Hanine Medani¹, Raida Ahmad¹, Rashpal Flora¹, Pritesh Trivedi¹, Alistair Reid¹, Kikkeri N Naresh¹

Affiliations

¹ Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
² Institute of Pathology, University Hospital Basel, Basel, Switzerland.

PMID: 27447126
DOI: 10.1111/bjh.14250

No abstract available

Keywords: MYC; diffuse large B-cell lymphoma; double-hit lymphomas; fluorescence in situ hybridization; immunohistochemistry.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Biomarkers, Tumor
Diagnostic Tests, Routine / methods
Disease Progression
Genetic Testing / methods
Humans
Lymphoma, B-Cell / diagnosis*
Lymphoma, B-Cell / genetics*
Neoplasm Grading
Proto-Oncogene Proteins c-bcl-2 / genetics*
Proto-Oncogene Proteins c-myc / genetics*
Workflow

Substances

Biomarkers, Tumor
Proto-Oncogene Proteins c-bcl-2
Proto-Oncogene Proteins c-myc