Spying on Cells: Toward a Perfect Sleeper Agent

Matthew D Wiens; Xiaocen Lu; Robert E Campbell

doi:10.1016/j.chembiol.2016.07.002

Spying on Cells: Toward a Perfect Sleeper Agent

Cell Chem Biol. 2016 Jul 21;23(7):756-758. doi: 10.1016/j.chembiol.2016.07.002.

Authors

Matthew D Wiens¹, Xiaocen Lu¹, Robert E Campbell²

Affiliations

¹ Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada.
² Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada. Electronic address: robert.e.campbell@ualberta.ca.

PMID: 27447045
DOI: 10.1016/j.chembiol.2016.07.002

Abstract

Creative engineering of fluorescent proteins has yielded a variety of tools for visualization of biochemical events in vivo. In this issue of Cell Chemical Biology, To et al. (2016) describe a fluorogenic green fluorescent protein that is activated by caspase-3 activity and enables imaging of apoptosis in developing zebrafish embryos (To et al., 2016).

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MeSH terms

Animals
Apoptosis*
Caspases*
Green Fluorescent Proteins
Zebrafish

Substances

Green Fluorescent Proteins
Caspases