In brief: About 4% of the athletes with foot problems seen by the authors had cuboid syndrome. The authors say the syndrome is common but that many cases are not recognized or are misdiagnosed. In their experience, it occurs most often in pronated feet, and pain results from a partial displacement of the cuboid, which prevents its normal range of motion. The pain is relieved by manipulating the cuboid to restore its normal position. A cuboid pad or low-dye strapping help prevent recurrences. Orthotics may be necessary to correct excessive pronation of the feet.