Fabrication of an Interlocked Antibiotic/Cement-Coated Carbon Fiber Nail for the Treatment of Long Bone Osteomyelitis

J Orthop Trauma. 2016 Aug:30 Suppl 2:S23-4. doi: 10.1097/BOT.0000000000000587.

Abstract

Successful management of intramedullary long bone osteomyelitis remains a challenge for both surgeons and patients. Patients are often immune compromised and have endured multiple surgeries. Treatment principles include antibiotic administration (systemically ± locally), surgical debridement of the infection site, and stabilization. Since their description in 2002, antibiotic-coated nails have become part of the armamentarium for the treatment of osteomyelitis allowing both local elution of antibiotics and stabilization of a debrided long bone. Limitations to their utilization have remained, in part from the technical difficulty of fabrication and magnetic resonance imaging artifacts. We describe a new surgical technique of fabrication that has the advantages of being simple, reproducible, with an end product free of magnetic resonance imaging artifacts.

Publication types

  • Review
  • Video-Audio Media

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Antibiotic Prophylaxis / methods*
  • Bone Cements / therapeutic use*
  • Bone Nails*
  • Carbon / chemistry
  • Carbon Fiber
  • Coated Materials, Biocompatible / administration & dosage
  • Combined Modality Therapy / instrumentation
  • Combined Modality Therapy / methods
  • Debridement / instrumentation
  • Debridement / methods
  • Drug Implants / administration & dosage*
  • Equipment Failure Analysis
  • Evidence-Based Medicine
  • Humans
  • Osteomyelitis / therapy*
  • Prosthesis Design
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Bone Cements
  • Carbon Fiber
  • Coated Materials, Biocompatible
  • Drug Implants
  • Carbon