A Touch of Youth in Gut Microbiota Development

Giuliana Magri; Andrea Cerutti

doi:10.1016/j.immuni.2016.07.002

A Touch of Youth in Gut Microbiota Development

Immunity. 2016 Jul 19;45(1):12-4. doi: 10.1016/j.immuni.2016.07.002.

Authors

Giuliana Magri¹, Andrea Cerutti²

Affiliations

¹ Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona Biomedical Research Park, 08003 Barcelona, Spain.
² Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona Biomedical Research Park, 08003 Barcelona, Spain; Catalan Institute for Research and Advanced Studies, Barcelona Biomedical Research Park, 08003 Barcelona, Spain; Division of Clinical Immunology, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: andrea.cerutti@mssm.edu.

PMID: 27438763
DOI: 10.1016/j.immuni.2016.07.002

Abstract

In a recent issue of Nature, Gordon and colleagues show that, during the first 2 years life, the assembly of the gut microbiota follows predictable architectural patterns that correlate with the development of commensal-specific immunoglobulin A responses.

Publication types

Comment

MeSH terms

Adult
Bacteria / immunology*
Gastrointestinal Microbiome / immunology*
Host-Pathogen Interactions
Humans
Immunoglobulin A / metabolism
Infant
Infant, Newborn
Inflammatory Bowel Diseases / immunology*
Inflammatory Bowel Diseases / microbiology
Intestinal Mucosa / immunology
Intestinal Mucosa / microbiology*
Risk
Symbiosis

Substances

Immunoglobulin A