[THE THROMBUS FORMATION IN THE PROSTHESIS AS A REACTION OF ORGANISM ON ITS MATERIAL]

T A Alekseyeva; Yu M Gupalo; A M Kolomoets; O N Lazarenko; G O Lazarenko; P M Litvin; I V Lohs; V J Smorzhevskiy; V I Stepkin

[THE THROMBUS FORMATION IN THE PROSTHESIS AS A REACTION OF ORGANISM ON ITS MATERIAL]

Klin Khir. 2016 Apr:(4):33-6.

[Article in Russian]

Authors

T A Alekseyeva, Yu M Gupalo, A M Kolomoets, O N Lazarenko, G O Lazarenko, P M Litvin, I V Lohs, V J Smorzhevskiy, V I Stepkin

PMID: 27434951

Abstract

Abstract Vascular prostheses, excised because of their functional properties loss, were studied. Using different methods there was established, that this complication is caused by the thrombus formation as a reaction of organism on the prosthesis material. The testing procedure on compatibility was proposed, using atomic-power microscope. Components of a patient immunity may identify the prosthesis material and start the rejection mechanisms in case of negative reaction.

Publication types

English Abstract

MeSH terms

Anastomosis, Surgical / instrumentation*
Biocompatible Materials / adverse effects*
Blood Coagulation / drug effects
Blood Vessel Prosthesis*
C-Reactive Protein / immunology
C-Reactive Protein / metabolism
Equipment Failure Analysis
Femoral Artery / pathology
Femoral Artery / surgery
Humans
Immunoglobulin G / blood
Materials Testing
Microscopy, Atomic Force
Polytetrafluoroethylene / adverse effects*
Popliteal Artery / pathology
Popliteal Artery / surgery
Prosthesis Failure*
Prosthesis Implantation
Retrospective Studies
Surface Properties
Thrombosis / etiology*
Thrombosis / immunology
Thrombosis / pathology
Thrombosis / surgery

Substances

Biocompatible Materials
Immunoglobulin G
Polytetrafluoroethylene
C-Reactive Protein