Changes in the antibiotic susceptibility of anaerobic bacteria from 2007-2009 to 2010-2012 based on the CLSI methodology

Christine J Hastey; Halsey Boyd; Audrey N Schuetz; Karen Anderson; Diane M Citron; Jody Dzink-Fox; Meredith Hackel; David W Hecht; Nilda V Jacobus; Stephen G Jenkins; Maria Karlsson; Cynthia C Knapp; Laura M Koeth; Hannah Wexler; Darcie E Roe-Carpenter; From the Ad Hoc Working Group on Antimicrobial Susceptibility Testing of Anaerobic Bacteria of CLSI

doi:10.1016/j.anaerobe.2016.07.003

Changes in the antibiotic susceptibility of anaerobic bacteria from 2007-2009 to 2010-2012 based on the CLSI methodology

Anaerobe. 2016 Dec:42:27-30. doi: 10.1016/j.anaerobe.2016.07.003. Epub 2016 Jul 15.

Authors

Christine J Hastey¹, Halsey Boyd¹, Audrey N Schuetz², Karen Anderson³, Diane M Citron⁴, Jody Dzink-Fox⁵, Meredith Hackel⁶, David W Hecht⁷, Nilda V Jacobus⁸, Stephen G Jenkins⁹, Maria Karlsson³, Cynthia C Knapp¹⁰, Laura M Koeth¹¹, Hannah Wexler¹², Darcie E Roe-Carpenter¹³; From the Ad Hoc Working Group on Antimicrobial Susceptibility Testing of Anaerobic Bacteria of CLSI

Affiliations

¹ Beckman Coulter Diagnostics, Inc., West Sacramento, CA, USA.
² Weill Cornell Medical College/New York-Presbyterian Hospital, New York, NY, USA.
³ Centers for Disease Control and Prevention Atlanta, GA, USA.
⁴ R.M. Alden Research Laboratory, Culver City, CA, USA.
⁵ Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
⁶ International Health Management Associates Inc., Schaumburg, IL, USA.
⁷ Loyola University Medical Center, Maywood, IL, USA.
⁸ Tufts Medical Center, Boston, MA, USA.
⁹ New York Presbyterian Hospital, New York, NY, USA.
¹⁰ Thermo Fisher Scientific, Cleveland, OH, USA.
¹¹ Laboratory Specialists, Inc. Westlake, OH, USA.
¹² UCLA School of Medicine, Westwood, CA, USA.
¹³ Beckman Coulter Diagnostics, Inc., West Sacramento, CA, USA. Electronic address: decarpenter@beckman.com.

Abstract

Antimicrobial susceptibility testing of anaerobic isolates was conducted at four independent sites from 2010 to 2012 and compared to results from three sites during the period of 2007-2009. This data comparison shows significant changes in antimicrobial resistance in some anaerobic groups. Therefore, we continue to recommend institutions regularly perform susceptibility testing when anaerobes are cultured from pertinent sites. Annual generation of an institutional-specific antibiogram is recommended for tracking of resistance trends over time.

Keywords: Anaerobe; Antibiogram; Antimicrobial susceptibility.

Publication types

Multicenter Study

MeSH terms

Anti-Bacterial Agents / pharmacology*
Bacteria, Anaerobic / classification
Bacteria, Anaerobic / drug effects*
Bacteria, Anaerobic / physiology
Bacterial Infections / drug therapy*
Bacterial Infections / epidemiology
Bacterial Infections / microbiology
Drug Resistance, Bacterial / physiology*
Humans
Microbial Sensitivity Tests
Retrospective Studies
United States / epidemiology

Substances

Anti-Bacterial Agents

Grants and funding

CC999999/Intramural CDC HHS/United States