(Salen)Mn(III) Catalyzed Asymmetric Epoxidation Reactions by Hydrogen Peroxide in Water: A Green Protocol

Int J Mol Sci. 2016 Jul 12;17(7):1112. doi: 10.3390/ijms17071112.

Abstract

Enantioselective epoxidation reactions of some chosen reactive alkenes by a chiral Mn(III) salen catalyst were performed in H₂O employing H₂O₂ as oxidant and diethyltetradecylamine N-oxide (AOE-14) as surfactant. This procedure represents an environmentally benign protocol which leads to e.e. values ranging from good to excellent (up to 95%).

Keywords: enantioselectivity; epoxidation; hydrogen peroxide; jacobsen catalyst; water.

MeSH terms

  • Alkenes / chemistry
  • Catalysis
  • Ethylenediamines / chemistry
  • Green Chemistry Technology
  • Hydrogen Peroxide / chemistry*
  • Organometallic Compounds / chemistry
  • Stereoisomerism
  • Surface-Active Agents / chemistry
  • Water / chemistry*

Substances

  • Alkenes
  • Ethylenediamines
  • Organometallic Compounds
  • Surface-Active Agents
  • Water
  • N,N'-bis(salicylideneamino)ethane-manganese(II)
  • Hydrogen Peroxide