Application of Chiral Ionic Liquid-Modified Gold Nanoparticles in the Chiral Recognition of Amino Acid Enantiomers

Lu Huang; Yi-Ting Chen; Yan-Xia Li; Li-Shuang Yu

doi:10.1177/0003702816645353

Application of Chiral Ionic Liquid-Modified Gold Nanoparticles in the Chiral Recognition of Amino Acid Enantiomers

Appl Spectrosc. 2016 Oct 1;70(10):1649-1654. doi: 10.1177/0003702816645353. Epub 2016 Jul 14.

Authors

Lu Huang¹, Yi-Ting Chen², Yan-Xia Li², Li-Shuang Yu³

Affiliations

¹ Department of Chemistry and Chemical Engineering, Minjiang University, Fuzhou, China luhuang@mju.edu.cn.
² Department of Chemistry and Chemical Engineering, Minjiang University, Fuzhou, China.
³ College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China.

PMID: 27418633
DOI: 10.1177/0003702816645353

Abstract

Two chiral ionic liquids (ILs), namely 1-ethyl-3-methylimidazole l-tartrate (EMIML-Tar) and 1-ethyl-3-methylimidazole l-lactate (EMIML-Lac), were used to modify gold nanoparticles (AuNPs) for chiral recognition of amino acid enantiomers. Transmission electron microscopy, infrared spectroscopy, ultraviolet-visible spectroscopy, and capillary electrophoresis were used for the characterization of chiral IL-modified AuNPs. Meanwhile, the performance of l-tartaric acid and l-lactic acid as modifiers was investigated to make a comparison. The chiral recognition mechanism is further discussed.

Keywords: Chiral ionic liquid; amino acid; chiral recognition; gold nanoparticles.