A direct-liquid-cooled side-pumped Nd:YAG multi-disk QCW laser resonator is presented, in which the oscillating laser propagates through multiple thin disks and cooling flow layers in Brewster angle. Twenty Nd:YAG thin disks side-pumped by LD arrays are directly cooled by flowing deuteroxide at the end surfaces. A laser output with the highest pulse energy of 17.04 J is obtained at the pulse width of 250 μs and repetition rate of 25 Hz, corresponding to an optical-optical efficiency of 34.1% and a slope efficiency of 44.5%. The maximum average output power of 7.48 kW is achieved at the repetition rate of 500 Hz. Due to thermal effects, the corresponding optical-optical efficiency decreases to 30%. Under the 12.5 kW pumping condition while not oscillating, the wavefront of a He-Ne probe passing through the gain module is as low as 0.256 μm (RMS) with the defocus and tetrafoil subtracted.