Myeloid Sarcoma: Presenting with Massive Cervical and Inguinal Lymphadenopathy

John C Walsh; Michelle G Arnold; Arash Mohtashamian

doi:10.1007/s12105-016-0742-5

Myeloid Sarcoma: Presenting with Massive Cervical and Inguinal Lymphadenopathy

Head Neck Pathol. 2017 Jun;11(2):219-223. doi: 10.1007/s12105-016-0742-5. Epub 2016 Jul 9.

Authors

John C Walsh¹, Michelle G Arnold², Arash Mohtashamian³

Affiliations

¹ Laboratory Department, Naval Medical Center San Diego, San Diego, CA, USA. John.C.Walsh26.mil@mail.mil.
² Department of Otolaryngology-Head and Neck Surgery, Naval Medical Center San Diego, San Diego, CA, USA.
³ Laboratory Department, Naval Medical Center San Diego, San Diego, CA, USA.

Abstract

A 21 year old Active Duty Marine presented with acute onset of diffuse lymphadenopathy and B-symptoms. Biopsy was conducted which demonstrated myeloid sarcoma. Myeloid sarcoma is diagnostic for AML but is only present in 2-8 % of patients with AML. Our article presents a classic presentation and histologic appearance and discusses the current status of the literature.

Keywords: AML; Acute myeloid leukemia; Chloroma; Extra-medullary myeloid tumor; Granulocytic sarcoma; Lymphadenopathy; Myeloid sarcoma.

Publication types

Case Reports

MeSH terms

Humans
Leukemia, Myeloid, Acute / complications
Leukemia, Myeloid, Acute / pathology*
Lymphadenopathy / etiology
Male
Sarcoma, Myeloid / complications
Sarcoma, Myeloid / pathology*
Young Adult