[Invasive yeast infections in neutropenic patients]

Abstract

Invasive fungal diseases caused by yeasts still play an important role in the morbidity and mortality in neutropenic patients with haematological malignancies. Although the overall incidence of invasive candidiasis has decreased due to widespread use of antifungal prophylaxis, the incidence of non-Candida albicans Candida species is increasing compared with that of C.albicans, and mortality of invasive candidiasis continues to be high. In addition, there has been an increase in invasive infections caused by an array of uncommon yeasts, including species of the genus Malassezia, Rhodotorula, Trichosporon and Saprochaete, characterised by their resistance to echinocandins and poor prognosis.

Keywords: Candidiasis invasora; Haematological malignancies; Infección invasora por levaduras; Invasive candidiasis; Invasive yeast infection; Malassezia; Neoplasias hematológicas; Neutropenia; Rhodotorula; Saprochaete; Trichosporon.