Abstract
Lasiodiplodia species are environmental fungi that have been reported as a cause of infection in both immunocompetent and immunocompromised patients. We present a case of fungal osteomyelitis caused by Lasiodiplodia species in a patient with multiple myeloma after autologous stem cell transplant. The patient was successfully treated with a combination of surgery and oral voriconzole. To the best of our knowledge, this is the first reported case of fungal osteomyelitis caused by Lasiodiplodia species.
Keywords:
Lasiodiplodia species; fungal osteomyelitis; multiple myeloma.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
MeSH terms
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Aged
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Amphotericin B / administration & dosage
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Amphotericin B / therapeutic use
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Amputation, Surgical
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Antifungal Agents / administration & dosage
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Antifungal Agents / therapeutic use*
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents / therapeutic use
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Ascomycota / isolation & purification*
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Biopsy
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Blood Cell Count
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Fatal Outcome
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Humans
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Immunocompromised Host
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Magnetic Resonance Imaging
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Male
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Multiple Myeloma / therapy*
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Osteomyelitis / blood
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Osteomyelitis / microbiology*
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Osteomyelitis / pathology
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Osteomyelitis / therapy*
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Skin / pathology
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Toes / pathology
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Transplantation, Autologous / adverse effects
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Treatment Refusal
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Voriconazole / administration & dosage
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Voriconazole / therapeutic use
Substances
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Antifungal Agents
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Antineoplastic Agents
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liposomal amphotericin B
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Amphotericin B
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Voriconazole